Botha has played Super Rugby and established a formidable reputation in the Guinness PRO14 before he signed for the Ospreys. He recently underwent an operation on his toe after picking up an injury against Saracens in the first round of the Heineken Champions Cup Pool.
He has set his sights on a return to fitness with the Ospreys in March.
"The Ospreys medical team have been awesome and have helped me immensely in managing and taking me through my rehab" said Botha.
"I am grateful for all of their help and guidance.
"I'm hoping to be back around the beginning of March and it has been frustrating not being able to play a part and not being able to help the boys and the team out.
"It's hard watching from the sidelines when all you want to do is get involved and play your part."
Dan Griffiths, Ospreys Rugby General Manager, said Botha's re-signing was a positive statement by the region.
"We signed Tom for his reputation as a powerful scrummager and he has certainly delivered in that area," said Griffiths.
"He is an honest, hard-working, experienced front row forward who always puts a shift in for us.
"We know how critical a solid platform at scrum time is for your attacking game, and the front row, as always, is an area you need a depth of resource and quality. Tom has provided us with that at tighthead and is a valuable member of the squad."
Tom Botha is sponsored by XBLOX